Erythema gyratum repens-like eruption in a patient with epidermolysis bullosa acquisita associated with ulcerative colitis.

نویسندگان

  • A España
  • C Sitaru
  • M Pretel
  • L Aguado
  • J Jimenez
چکیده

SIR, Epidermolysisbullosaacquisita (EBA) is an acquired auto-immune bullous disease of the skin and mucous membranes characterized by IgG autoantibodies to type VII collagen, the main constituent of the anchoring fibrils of the dermal– epidermal juction. Inflammatory bowel diseases (IBD) may be associated with autoimmunity to type VII collagen. Erythema gyratumrepens (EGR), an obligate paraneoplastic syndrome, may occur in patients with pemphigoid diseases. To the best of our knowledge, EGR has not been previously described in EBA. We report a most unusual clinical manifestation of EGR-like lesions in a patient with EBA and ulcerative colitis (UC).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The epidermolysis bullosa acquisita antigen (type VII collagen) is present in human colon and patients with crohn's disease have autoantibodies to type VII collagen.

Epidermolysis bullosa acquisita is an autoimmune blistering disease of the skin characterized by IgG autoantibodies against type VII collagen. Systemic diseases are often associated with epidermolysis bullosa acquisita, Crohn's disease being the most frequent. This study sought to determine if type VII collagen, the epidermolysis bullosa acquisita autoantigen, was present in normal human colon ...

متن کامل

Generalized granuloma annulare with clinical presentation resembling Erythema Gyratum Repens in a diabetic female patient

Generalized granuloma (GA) is an inflammatory benign cutaneous disease of unknown etiology that may manifest different clinical features. The most common presentation or classic form of the disease is flesh colored, annular, grouped papules. They usually are on the extremities especially on the lateral or dorsal surfaces of the fingers, hands, wrists, ankles, and insteps. Several clinical manif...

متن کامل

Erythema Gyratum Repens-Like Purpura in a Patient with Sjögren Syndrome

The etiology of purpura in Sjögren syndrome (SS) includes cryoglobulinemia, hypergammaglobulinemia, and leukocytoclastic vasculitis (LCV). The clinical symptoms of LCV associated with SS comprise palpable or nonpalpable purpura and urticarial vasculitis. Here, we report a case of LCV presenting as erythema gyratum repens (EGR)-like purpura in a 62-year-old woman with rheumatoid arthritis and SS...

متن کامل

Acute renal failure in a patient with epidermolysis bullosa acquisita*

Epidermolysis bullosa acquisita is a severe autoimmune subepidermal bullous disease. In this report, we described for the first time a patient with epidermolysis bullosa acquisita who developed acute renal failure. There is a possibility that epidermolysis bullosa acquisita and acute renal failure's pathogenesis shared some common autoimmune pathways. Moreover, acute blood volume reduction may ...

متن کامل

Epidermolysis bullosa acquisita and Crohn's disease.

A patient with epidermolysis bullosa acquisita (EBA) associated with Crohn's disease is presented. The clinical, histological and immunological findings were in keeping with previous reports. However, clinically normal skin and mucosa exhibited deposits of IgG and C3 in the basement-membrane zone. These deposits remained unchanged during the treatment period. It is therefore suggested that immu...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The British journal of dermatology

دوره 156 4  شماره 

صفحات  -

تاریخ انتشار 2007